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Seasons Sequences: Closing the year with Chromatin

2024-01-08T22:58:41+00:00January 8, 2024|3D Genomics, Epigenetics, Hi-C, HiChIP, Micro-C, Omni-C, Uncategorized|

Seasons Sequences: Closing the Year with Chromatin  After a wet arrival, the rain broke, and the sun finally made an appearance, marking the second day of the historic 45th annual Asilomar Chromatin Conference – yes, you read that right, 45 years! Despite chilly temperatures, [...]

Herbicide Resistance in Blackgrass, Was It There All Along?

2023-12-29T21:48:38+00:00December 29, 2023|3D Genomics, Epigenetics, Hi-C, HiChIP, Micro-C, Omni-C, Uncategorized|

Herbicide Resistance in Blackgrass, Was It There All Along? In the realm of agriculture, the ongoing battle against herbicide-resistant weeds presents a persistent challenge. The emergence of spontaneous mutants with herbicide resistance in weed populations poses a grave threat to crop yields and food [...]

Genomic Research in Service of Conservation: The Cases of Whitebark Pine and Clark’s Nutcracker

2023-12-29T21:52:16+00:00December 5, 2023|3D Genomics, Epigenetics, Hi-C, HiChIP, Micro-C, Omni-C, Uncategorized|

Genomic Research in Service of Conservation: The Cases of Whitebark Pine and Clark's Nutcracker The Interdependent Lives of Whitebark Pine and Clark's Nutcracker The mutual relationship between the whitebark pine and Clark's Nutcracker, as detailed by the National Park Service, provides a compelling context for [...]

Demystifying Hi-C Data Normalization: A Guide for Genomic Researchers

2023-12-29T21:54:42+00:00November 3, 2023|3D Genomics, Epigenetics, Hi-C, HiChIP, Micro-C, Omni-C, Uncategorized|

Demystifying Hi-C Data Normalization: A Guide for Genomic Researchers Genomic research has come a long way since the draft of the human genome was first published over two decades ago, driven by the continuous advancements in next-generation sequencing (NGS) technologies. One of the most [...]

What Is Enhancer Hijacking, And How Can I Detect It?

2023-07-11T19:44:42+00:00July 11, 2023|3D Genomics, Epigenetics, Hi-C, HiChIP, Micro-C, Omni-C, Uncategorized|

What Is Enhancer Hijacking, And How Can I Detect It? Active gene expression requires the coordinated interaction between gene promoters and genetic elements called enhancers. Enhancers are DNA sequences that are often located at great distances in linear sequence from the genes they regulate, but physically interact [...]

Enrich Your Understanding of Gene Expression with Promoter Capture Hi-C

2022-06-17T16:26:23+00:00July 7, 2021|Hi-C, HiChIP|

Enrich Your Understanding of Gene Expression with Promoter Capture Hi-C If you haven’t heard the news yet, the Dovetail Genomics® team recently launched a new product line for Target Enrichment of Dovetail® proximity ligation libraries. Our first two products are Pan [...]

Keystone eSymposia Highlights

2022-02-23T06:09:51+00:00June 1, 2021|Epigenetics, Hi-C, Micro-C|

Epigenetics, Chromatin Architecture, Development and Disease… Oh my!  Keystone eSymposia Highlights The Keystone series of conferences has not only become synonymous with their picturesque location and intimate atmosphere but also the scientific passion attendees bring to each conference. [...]

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Why Settle for Half a Genome?

2022-02-23T06:09:51+00:00May 14, 2021|Hi-C, HiChIP|

The tools available for capturing genomic information have evolved dramatically over the past decade, yet plant and animal reference genomes remain haploid. Through advances in Dovetail® proximity ligation (Hi-C) technology, the capture of genetic variation along with ultra-long-range genomic sequence information in a single assay is now possible. A [...]

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