Epigenetics – HiChIP MNase Service
Catalog # 20017

Why Use Our Service
• Discover enhancer-promoter interactions controlling expression of your gene of interest – Uncover not just where proteins bind, but also the long-range interactions they mediate
• Get ultra-high nucleosome-level resolution of chromatin contacts – MNase generates nucleosome length (146 bp) fragments and proximity ligation is optimized to maximize long-range interaction
• With protein-directed enrichment, boost your signal-to-noise and enrichment of long-range informative reads
• Add meaning to your ChIP-seq data by uncovering the interactome associated with your protein of interest
How It Works
Your designated Scientific Project Manager will work with you to understand your goals and define deliverables specific to your project. We can complete your project from beginning to end or just perform part of it – it’s totally up to you!
Just prep your samples using our best practices for transfer using the best practices guidelines we’ve established, send us your mammalian cells, tissue, or blood samples, and sit back while our Hi-C experts do the work for you! Once we receive your sample(s), your Scientific Project Manager will keep you informed of our progress as we hit each project milestone.
Learn more about the HiChIP MNase Kit
Specifications
Delivery Time | 10 weeks from sample to completed analysis |
Sample Type | Human or mouse cells, tissue, or blood |
Library Generation | Dovetail Hi-C |
Sequencing Platform | Illumina |
Analysis Platform | Dovetail QC pipeline |
Available Antibodies | CTCF, H3K4me3, or H3K27ac (IgG available as a negative control) |
Available Add-On | ChIP-seq MNase Service |
Potential Deliverables | QC Report Sequence data (*.fastq file format) Alignment (.bam format) Contact matrices (*.mcool and *.hic file formats) Pairs file (.pair format) |