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Demystifying Hi-C Data Normalization: A Guide for Genomic Researchers

2023-11-03T23:06:05+00:00November 3, 2023|3D Genomics, Epigenetics, Hi-C, HiChIP, Micro-C, Omni-C, Uncategorized|

Demystifying Hi-C Data Normalization: A Guide for Genomic Researchers Genomic research has come a long way since the draft of the human genome was first published over two decades ago, driven by the continuous advancements in next-generation sequencing (NGS) technologies. One of the most [...]

What Is Enhancer Hijacking, And How Can I Detect It?

2023-07-11T19:44:42+00:00July 11, 2023|3D Genomics, Epigenetics, Hi-C, HiChIP, Micro-C, Omni-C, Uncategorized|

What Is Enhancer Hijacking, And How Can I Detect It? Active gene expression requires the coordinated interaction between gene promoters and genetic elements called enhancers. Enhancers are DNA sequences that are often located at great distances in linear sequence from the genes they regulate, but physically interact [...]

Boston Epigenetics Society – Review

2023-09-09T20:39:26+00:00December 6, 2021|3D Genomics, Epigenetics, HiChIP, Micro-C, Uncategorized|

What Do You Get When Academia and Industry Come Together To Discuss Epigenetics? November 16th marked the inaugural meeting of the newly formed Boston Epigenetics Society. With over 800 scientists in attendance to learn about the latest research from Dr. David Sinclair, Professor in the Department of Genetics, [...]

DT-Epi Summit Brings Together Scientists From Across The Globe

2022-06-20T18:07:43+00:00September 30, 2021|3D Genomics, Epigenetics, Hi-C, HiChIP, Micro-C|

DT-Epi Summit Brings Together Scientists From Across The Globe On September 15th, Dovetail Genomics held its first Epigenetics Summit (DT-Epi 2021) on how nucleosome-based approaches have advanced our understanding of chromatin conformation and its role in gene regulation. “Fast, furious, and loud” were some of the words used [...]

Enrich Your Understanding of Gene Expression with Promoter Capture Hi-C

2022-06-17T16:26:23+00:00July 7, 2021|Hi-C, HiChIP|

Enrich Your Understanding of Gene Expression with Promoter Capture Hi-C If you haven’t heard the news yet, the Dovetail Genomics® team recently launched a new product line for Target Enrichment of Dovetail® proximity ligation libraries. Our first two products are Pan [...]

Why Settle for Half a Genome?

2022-02-23T06:09:51+00:00May 14, 2021|Hi-C, HiChIP|

The tools available for capturing genomic information have evolved dramatically over the past decade, yet plant and animal reference genomes remain haploid. Through advances in Dovetail® proximity ligation (Hi-C) technology, the capture of genetic variation along with ultra-long-range genomic sequence information in a single assay is now possible. A [...]

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