Demystifying Hi-C Data Normalization: A Guide for Genomic Researchers Genomic research has come a long way since the draft of the human genome was first published over two decades ago, driven by the continuous advancements in next-generation sequencing (NGS) technologies. One of the most [...]
What Is Enhancer Hijacking, And How Can I Detect It? Active gene expression requires the coordinated interaction between gene promoters and genetic elements called enhancers. Enhancers are DNA sequences that are often located at great distances in linear sequence from the genes they regulate, but physically interact [...]
What Do You Get When Academia and Industry Come Together To Discuss Epigenetics? November 16th marked the inaugural meeting of the newly formed Boston Epigenetics Society. With over 800 scientists in attendance to learn about the latest research from Dr. David Sinclair, Professor in the Department of Genetics, [...]
DT-Epi Summit Brings Together Scientists From Across The Globe On September 15th, Dovetail Genomics held its first Epigenetics Summit (DT-Epi 2021) on how nucleosome-based approaches have advanced our understanding of chromatin conformation and its role in gene regulation. “Fast, furious, and loud” were some of the words used [...]
Enrich Your Understanding of Gene Expression with Promoter Capture Hi-C If you haven’t heard the news yet, the Dovetail Genomics® team recently launched a new product line for Target Enrichment of Dovetail® proximity ligation libraries. Our first two products are Pan [...]
The tools available for capturing genomic information have evolved dramatically over the past decade, yet plant and animal reference genomes remain haploid. Through advances in Dovetail® proximity ligation (Hi-C) technology, the capture of genetic variation along with ultra-long-range genomic sequence information in a single assay is now possible. A [...]
What’s Involved In Running A Dovetail® HiChIP Assay? (Part 2) You’ve generated your HiChIP libraries, had them sequenced, and are now wondering what to do with your data. Don’t worry, we will walk you through the process step by step and [...]
What’s Involved In Running A Dovetail® HiChIP Assay? (Part 1) Thinking about using the
Going Beyond ChIP-seq ‘Tis the holiday season and whether or not you’re awaiting a visit from that tubby fella with the white beard, you may have added ChIP-seq to your holiday wish list. ChIP-seq, of course, has become an indispensable tool for investigating [...]
