We are currently experiencing the planet’s sixth mass extinction event. The preservation of biological diversity could be considered as the single most important responsibility of mankind. As human-based pressures continue to threaten natural ecosystems, there has never been a greater need for actionable tools to monitor, preserve and enhance biodiversity.
A high-quality genome assembly is a crucial tool for conservation biologists striving to preserve threatened or at-risk species. An accurate and contiguous genome assembly can assist in the study of:
- Inbreeding depression
- Admixture and introgression
- Maintenance of population diversity
- Hybrid speciation
- Disease susceptibility
- Behavioral ecology
- Identification of adaptive alleles
- Genetic rescue
Proximity ligation is key to creating chromosome length assemblies
While long-read sequencing platforms are improving assembly contiguity over short-read sequencing, they are still not sufficient enough to reach chromosome-scale for all but the smallest of genomes. Dovetail Genomics® delivers the resolution you need, using our proprietary Hi-C technology to apply proximity ligation to non-model organism de novo genome assembly. Our scientific experts have delivered more than 1,600 high-quality genomes for a wide variety of unique species to advance the research for hundreds of researchers. Many of these assemblies offer key insights aiding species conservation efforts around the globe.
Harness Dovetail® proximity ligation expertise to start your conservation efforts through our kits or services
Dovetail Genomics has a solution for you. Bring proximity ligation into your own lab or outsource your genome assembly to our experts. Our Dovetail® Omni-C® Kit offers the most complete view of the genome available capturing long-range information alongside uniform base coverage. This unique datatype enables:
- Full-length genome assemblies
- Ability to phase diploid organism’s SNPs according to haplotype
Prefer to outsource to the experts? Our best-in-class service offerings support sample to publication.
- Build your draft assembly using industry-leading PacBio HiFi data
- Improve contiguity by scaffolding with Omni-C technology
- Make your genome actionable with our comprehensive annotation services