Dovetail^® Hi-C solutions all use sequence-independent nucleases to deliver high resolution and uniform base-coverage, and a novel dual cross-linking approach to enrich for long-range interactions. Our optimized, reproducible, off the shelf kits are validated across a wide range of samples and species and are ready to use so there’s no reagent qualification required. Choose the best kit for your research and take your discovery to the next dimension.

For those looking to add Hi-C to your ChIP-seq. Explore how primary protein binding and protein-mediated chromatin interactions influence gene expression – in a single library. It’s ChiP-Seq, just with 3D interaction information.

For those looking for fine-scale topology mapping down to the mono-nucleosome level (150 – 200 bp conformation). Unlock your genome architecture one nucleosome at a time.

For those looking to save on Hi-C experiment costs. Higher signal-to-noise ratios at 1 kbp conformation resolution translates to confident matrices building at just a fraction of the cost.

For those looking for uniform, shotgun-like sequence coverage to enable genotyping and haplotype phasing. Unravel 3D genome architecture and explore genetic variants and phased genomes from a single library.

For those looking to perform capture Hi-C. Save sequencing costs by targeted the pre-selected genomics region of interest to facilitate Hi-C studies on a large sample cohort.