Demystifying Hi-C Data Normalization: A Guide for Genomic Researchers Genomic research has come a long way since the draft of the human genome was first published over two decades ago, driven by the continuous advancements in next-generation sequencing (NGS) technologies. One of the most [...]
What Is Enhancer Hijacking, And How Can I Detect It? Active gene expression requires the coordinated interaction between gene promoters and genetic elements called enhancers. Enhancers are DNA sequences that are often located at great distances in linear sequence from the genes they regulate, but physically interact [...]
What Do You Get When Academia and Industry Come Together To Discuss Epigenetics? November 16th marked the inaugural meeting of the newly formed Boston Epigenetics Society. With over 800 scientists in attendance to learn about the latest research from Dr. David Sinclair, Professor in the Department of Genetics, [...]
DT-Epi Summit Brings Together Scientists From Across The Globe On September 15th, Dovetail Genomics held its first Epigenetics Summit (DT-Epi 2021) on how nucleosome-based approaches have advanced our understanding of chromatin conformation and its role in gene regulation. “Fast, furious, and loud” were some of the words used [...]
Epigenetics, Chromatin Architecture, Development and Disease… Oh my! Keystone eSymposia Highlights The Keystone series of conferences has not only become synonymous with their picturesque location and intimate atmosphere but also the scientific passion attendees bring to each conference. [...]
What’s Involved In Running A Dovetail Hi-C Assay? (Part 1) So you are interested in bringing Hi-C into your lab! What is involved in getting the assay up and running? This is the first in a series of blogs that explain how to run [...]
What is a Dovetail® Service Project? It is a good time to consider getting a Dovetail service project when... 1. The sample is ready, but you don’t seem to be able to get to it. 2. You are uncertain of how [...]
Chromatin conformation capture (3C) assays have been used for ~20 years to elucidate complex folding of genomic sequence in three-dimensional space.