What Is Enhancer Hijacking, And How Can I Detect It? Active gene expression requires the coordinated interaction between gene promoters and genetic elements called enhancers. Enhancers are DNA sequences that are often located at great distances in linear sequence from the genes they regulate, but physically interact [...]
Chromatin Epigenetics Comes to Victoria BC With its majestic lines and stunning outlook over Victoria Harbor, attending a conference at the Fairmont Empress Victoria might appear to be more “junket” than serious forum for the exchange of scientific ideas – but that would be a gross misrepresentation. As [...]
The benefits of a haplotype-resolved (true diploid) genome assembly De novo genome assemblies have traditionally been pseudo-haploid in nature. Newer, more accurate long read sequencing coupled with unbiased, restriction-enzyme-free proximity ligation technology is enabling high-quality haplotype-phased genome assemblies from a single individual. Phased haplotype blocks are now of [...]
Saving Our Endangered Species One Genome At A Time Revive & Restore (R&R) and Dovetail Genomics (DTG) co-sponsored their inaugural Conservation Genomics Summit on October 27, 2021. This virtual event brought six prominent conservation biologists together with an audience of more than 350 to discuss the application of [...]
DT-Epi Summit Brings Together Scientists From Across The Globe On September 15th, Dovetail Genomics held its first Epigenetics Summit (DT-Epi 2021) on how nucleosome-based approaches have advanced our understanding of chromatin conformation and its role in gene regulation. “Fast, furious, and loud” were some of the words used [...]
Enrich Your Understanding of Gene Expression with Promoter Capture Hi-C If you haven’t heard the news yet, the Dovetail Genomics® team recently launched a new product line for Target Enrichment of Dovetail® proximity ligation libraries. Our first two products are Pan [...]
Epigenetics, Chromatin Architecture, Development and Disease… Oh my! Keystone eSymposia Highlights The Keystone series of conferences has not only become synonymous with their picturesque location and intimate atmosphere but also the scientific passion attendees bring to each conference. [...]
The tools available for capturing genomic information have evolved dramatically over the past decade, yet plant and animal reference genomes remain haploid. Through advances in Dovetail® proximity ligation (Hi-C) technology, the capture of genetic variation along with ultra-long-range genomic sequence information in a single assay is now possible. A [...]
What’s Involved In Running A Dovetail® HiChIP Assay? (Part 2) You’ve generated your HiChIP libraries, had them sequenced, and are now wondering what to do with your data. Don’t worry, we will walk you through the process step by step and [...]
What’s Involved In Running A Dovetail® HiChIP Assay? (Part 1) Thinking about using the
