Demystifying Hi-C Data Normalization: A Guide for Genomic Researchers Genomic research has come a long way since the draft of the human genome was first published over two decades ago, driven by the continuous advancements in next-generation sequencing (NGS) technologies. One of the most [...]
What Is Enhancer Hijacking, And How Can I Detect It? Active gene expression requires the coordinated interaction between gene promoters and genetic elements called enhancers. Enhancers are DNA sequences that are often located at great distances in linear sequence from the genes they regulate, but physically interact [...]
Chromatin Epigenetics Comes to Victoria BC With its majestic lines and stunning outlook over Victoria Harbor, attending a conference at the Fairmont Empress Victoria might appear to be more “junket” than serious forum for the exchange of scientific ideas – but that would be a gross misrepresentation. As [...]
The benefits of a haplotype-resolved (true diploid) genome assembly De novo genome assemblies have traditionally been pseudo-haploid in nature. Newer, more accurate long read sequencing coupled with unbiased, restriction-enzyme-free proximity ligation technology is enabling high-quality haplotype-phased genome assemblies from a single individual. Phased haplotype blocks are now of [...]
What Do You Get When Academia and Industry Come Together To Discuss Epigenetics? November 16th marked the inaugural meeting of the newly formed Boston Epigenetics Society. With over 800 scientists in attendance to learn about the latest research from Dr. David Sinclair, Professor in the Department of Genetics, [...]
Saving Our Endangered Species One Genome At A Time Revive & Restore (R&R) and Dovetail Genomics (DTG) co-sponsored their inaugural Conservation Genomics Summit on October 27, 2021. This virtual event brought six prominent conservation biologists together with an audience of more than 350 to discuss the application of [...]
DT-Epi Summit Brings Together Scientists From Across The Globe On September 15th, Dovetail Genomics held its first Epigenetics Summit (DT-Epi 2021) on how nucleosome-based approaches have advanced our understanding of chromatin conformation and its role in gene regulation. “Fast, furious, and loud” were some of the words used [...]
