The Benefits of a Haplotype-Resolved (True Diploid) Genome Assembly
The benefits of a haplotype-resolved (true diploid) genome assembly De novo genome assemblies have traditionally been pseudo-haploid in nature. Newer, more accurate long read sequencing coupled with unbiased, restriction-enzyme-free proximity ligation technology is enabling high-quality haplotype-phased genome assemblies from a single individual. Phased haplotype blocks are now of [...]