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Products & Services Literature

Webinars & Videos

3-D Epigenetics

Capture genome architecture down to mono-nucleosome resolution using the Dovetail™ Micro-C Kit

Intro to Dovetail™ Micro-C™ Technology

3-D Epigenetics

From 3-D Genome Topology to SNPs: Omni C™ Kit provides a multi-resolution view of the genome in a single library prep

Intro to Dovetail™ Omni-C™ Technology

3-D Epigenetics

Analyze Protein-Directed Chromatin Architecture with the Dovetail™ HiChIP MNase Kit

Intro to Dovetail™ HiChIP MNase Technology


Dovetail Genomics:

The Genome Redefined

Company and Technology Overview Video

Genome Assembly

The Genes in the Beans: High-quality reference genomes provide tools for coffee breeding improvement

Dr. Susan Strickler, PhD 
Boyce Thompson Institute

Genome Assembly

Enabling non-model organism genomics with multidimensional NGS

Ellie Armstrong, PhD Candidate
Stanford University

Genome Assembly

The American Alligator: High-Quality Genome Assemblies for Non-Model Organisms

Dr. Richard Green, PhD 
UCSC; Dovetail Genomics

Genome Assembly

Disruptive Technologies for Improving Disease Resistance in Crop Plants

Dr. Richard Michelmore, PhD 
University of  California, Davis


Micro-C: Data Processing

Data Processing for Dovetail® Micro-C Assay

HiChIP: Data Processing

Data Processing for Dovetail® HiChIP MNase Assay

Data Processing

Dovetail® Proximity Ligation Data Processing

HiChIP: Wet Lab

What is involved in running a Dovetail® HIChIP MNase Assay?

Micro-C: Wet Lab

What is involved in running a Dovetail™ Micro-C Assay?

Grinding Plant Tissue

How to Grind Plant Tissue for Use in the Dovetail Kits

Contact Matrices

How to Generate Contact Matrices with RE-Free Data

Data QC

How to QC Dovetail Genomics RE-Free Hi-C Data

Grind Animal Tissue

How to Perform Automated Mammalian Tissue Grinding

In the News

  • Fix-C and Selva for SV Release
  • Dovetail Hi-C Kit release
  • Ramesh Head R&D
  • Tree Code Distributor
  • Daon Distributor Announcement
  • PacBio Sequencing Added
  • Coffee Genome Assembly
  • Long-Range Data


A chromosome-scale reference genome of trifoliate orange (Poncirus trifoliata) provides insights into disease resistance, cold tolerance and genome evolution in Citrus
Peng Z et al. The Plant Journal. 2020 September 27.

A chromosome-level assembly of the black tiger shrimp (Penaeus monodon) genome facilitates the identification of novel growth-associated genes
Uengwetwanit T et al. 2020 May 16. * Pre-print

A genome assembly of the barley ‘transformation reference’ cultivar Golden Promise
Schreiber M et al. G3: Genes, Genomes, Genetics. 2020 April 3.

De novo assembly of the cattle reference genome with single-molecule sequencing
Rosen BD et al. GigaScience. 2020 March 19.

Chromosomal‐level reference genome of the incense tree Aquilaria sinensis
Nong W et al. Molecular Ecology Resources. 2020 March 10.

Chromosome-Level Assembly of the Caenorhabditis remanei Genome Reveals Conserved Patterns of Nematode Genome Organization
Teterina AA, Willis JH, Phillips PC. Genetics. 2020 February 28.

Widespread Recombination Suppression Facilitates Plant Sex Chromosome Evolution
Rifkin JL et al.*Pre-Print. 2020 February 7.

Long live the king: chromosome-level assembly of the lion (Panthera leo) using linked-read, Hi-C, and long-read data
Armstrong EE et al. BMC Biology. 2020 January 8. 

The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins
Suryamohan S et al. Nature Genetics. 2020 January 6. 

A draft genome sequence of the elusive giant squid, Architeuthis dux
da Fonseca RR et al. GigaScience. 2020 January 1. 

*Pre-print articles available on bioRxiv

Genetic architecture drives seasonal onset of hibernation in the 13-lined ground squirrel
Grabek KR et al. Communications Biology. 2019 December 20.

Dichotomy of Dosage Compensation along the Neo Z Chromosome of the Monarch Butterfly
Gu L et al. Current Biology. 2019 December 2.

A Highly Contiguous Reference Genome for Northern Bobwhite (Colinus virginianus)
Salter JF et al. G3: GENES, GENOMES, GENETICS. 2019 December 1.

Genomic insights from the first chromosome-scale assemblies of oat (Avena spp.) diploid species
Maughan PJ et al. BMC Biology. 2019 November 22.

Towards an adaptive and genomic understanding of an exaggerated secondary sexual trait in water striders
Toubiana W. Biodiversity. Université de Lyon. 2019 November 12.

Assembly, annotation, and comparison of Macrophomina phaseolina isolates from strawberry and other hosts
Burkhardt AK et al. BMC Genomics. 2019 November 4.

Genome sequence and analysis of the eggplant (Solanum melongena L.)
Li D et al. 2019 October 31; *Pre-Print

The Major Histocompatibility Complex of Old World Camels-A Synopsis
Plasil M et al. Cells. 2019 October 5.

Haplotype-resolved genomes of geminivirus-resistant and geminivirus-susceptible African cassava cultivars
Kuon J et al. BMC Biology. 2019 September 18.

Author Correction: Improved reference genome for the domestic horse increases assembly contiguity and composition
Kalbfleisch Ts et al. Nature Communications. 2019 September 11.

Old World camels in a modern world – a balancing act between conservation and genetic improvement
Burger PA, Ciani C, Faye B. Animal Genetics. 2019 September 18.

The Komodo dragon (Varanus komodoensis) genome and identification of innate immunity genes and clusters
van Hoek ML et al. BMC Genomics. 2019 August 30.

The draft genome sequence of the spider Dysdera silvatica (Araneae, Dysderidae): A valuable resource for functional and evolutionary genomic studies in cheliceratess
Francisco Sánchez-Herrero J et al. Giga Science. 2019 August 20.

De Novo Genome Sequence Assembly of Dwarf Coconut (Cocos nucifera L. ‘Catigan Green Dwarf’) Provides Insights into Genomic Variation Between Coconut Types and Related Palm Species
Lantican DV et al. G3: GENES, GENOMES, GENETICS. 2019 August 9.

An integrated chromosome-scale genome assembly of the Masai giraffe (Giraffa camelopardalis tippelskirchi)
Farre M et al. GigaScience. 2019 July 30.

The Caribou (Rangifer tarandus) Genome
Taylor RS et al. Genes. 2019 July 17.

A high-quality genome of Eragrostis curvula grass provides insights into Poaceae evolution and supports new strategies to enhance forage quality
Carballo J et al. Scientific Reports. 2019 July 15.

Improving Illumina assemblies with Hi-C and long reads: An example with the North African dromedary
Elbers JP et al. Mol Ecol Resour. 2019 July.

Chromosome-Level Alpaca Reference Genome VicPac3.1 Improves Genomic Insight Into the Biology of New World Camelids
Richardson MF et al. Front. Genet. 2019 June 21.

Aquatic Adaptation and Depleted Diversity: A Deep Dive into the Genomes of the Sea Otter and Giant Otter
Beichman AC et al. Molecular Biology and Evolution. 2019 June 18.

Gene Family Evolution in the Pea Aphid Based on Chromosome-Level Genome Assembly
Lin Y, Park H, Smith TE, Moran NA. Molecular Biology and Evolution. 2019 June 7.

Modern technologies and algorithms for scaffolding assembled genomes
Ghurye J, Pop M. PLOS Computational Biology. 2019 June 5.

The Draft Genome of Eggplant
Hirakawa H. The Eggplant Genome. 2019 May 31.

Structural Variation Detection by Proximity Ligation from Formalin-Fixed, Paraffin-Embedded Tumor Tissue
Troll CJ et al. J Mol Diagn. 2019 May.

Improving Illumina assemblies with Hi‐C and long reads: An example with the North African dromedary
Elbers JP et al. Molecular Ecology Resources. 2019 April 11.

Origin and evolution of the octoploid strawberry genome
Edgar PP et al. Nat Genet. 2019 April.

A reference-grade wild soybean genome
Xie M et al. Nature Communications. 2019 March 14.

Haplotype-phased genome and evolution of phytonutrient pathways of tetraploid blueberry
Colle M. GigaScience. 2019 March 3.

A critical comparison of technologies for a plant genome sequencing project
Paajanen P. GigaScience. 2019 March 1.

Haplotype-phased genome and evolution of phytonutrient pathways of tetraploid blueberry
Colle M et al. GigaScience. 2019 March 1.

The new bovine reference genome assembly provides new insight into genomic organization of the bovine major histocompatibility complex
Zorc M, Ogorevc J, Dovc P. Journal of Central European Agriculture. 2019.

Symbiotic organs shaped by distinct modes of genome evolution in cephalopods
Belcaid M et al. PNAS. 2019 February 19.

New Approaches for Genome Assembly and Scaffolding
Rice ES, Green RE. Annu Rev Anim Biosci. 2019 February 15.

Chromosome-level assembly of the water buffalo genome surpasses human and goat genomes in sequence contiguity
Low WY et al. Nature Communications. 2019 January 16.

*Pre-print articles available on bioRxiv

Comparative analysis of the Pocillopora damiconis genome highlights roles of immune system in coral evolution
Cunning R et al. Scientific Reports. 2018 October 31.

Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci
Lilue J et al. Nature Genetics. 2018 October 1.

The genome of the oyster Saccostrea offers insight into the environmental resilience of bivalves 
Powell D et al. DNA Research. 2018 August 31.

Chicago® and Dovetail™ Hi-C proximity ligation yield chromosome length scaffolds of Ixodes scapularis genome
Nuss AB et al. 2018 August 15; Pre-print*.

High quality whole genome sequence of an abundant Holarctic odontocete, the harbour porpoise (Phocoena phocoena)
Autenrieth M et al. Molecular Ecology Resources. 2018 July 23.

Stout camphor tree genome fills gaps in understanding of flowering plant genome and gene family evolution
Chaw SM et al. 2018 July 18; Pre-print*.

Chromosome-scale comparative sequence analysis unravels molecular mechanisms of genome evolution between two wheat cultivars
Thind AK et al. BMC Genome Biology. 2018 July 10.

Decimation by sea star wasting disease and rapid genetic change in keystone species, Pisaster ochracceus 
Schiebelhut LM et al. Proc Natl Acad Sci U S A. 2018. pii: 201800285. doi: 10.1073/pnas.1800285115. 

A High-Quality Reference Genome for the Invasive Mosquitofish Gambusia affinis Using a Chicago Library
Hoffberg SL et al. G3 (Bethesda). 2018 May 31.

The African Bullfrog (Pyxicephalus adspersus) genome unites the two ancestral ingredients for making vertebrate sex chromosomes
Denton RD et al. G3 (Bethesda). 2018 May 24; Pre-print*.

Improved Genome Assembly and Annotation for the Rock Pigeon (Columba livia)
Holt C et al. G3 (Bethesda). 2018 May 4.

HImproved de novo genomic assembly for the domestic donkey
Renaud G et al. Sci Adv. 2018 April 4.

Hologenomic adaptations underlying the evolution of sanguivory in the common vampire bat
Medoza MLZ et al. Nat Ecol Evol. 2018 April.

EquCab3, an Updated Reference Genome for the Domestic Horse
Kalbfleisch TS et al. 2018 April 25; Pre-print*.

The sea lamprey germline provides insights into programmed genome rearrangements and vertebrate evolution
Smith JJ et al. Nat Genet. 2018 February;50(2):270-277. doi: 10.1038/s41588-017-0036-1.

The genome of Schmidtea mediterranea and the evolution of core cellular mechanisms
Grohme MA et al. Nature. 2018 February 1. 

Whole-genome assembly of the coral reef Pearlscale Pygmy Angelfish (Centropyge vrolikii)
Fernandez-Silva I et al. Sci Rep. 2018 January 24;8(1):1498. doi: 10.1038/s41598-018-19430-x.

The draft genome of tropical fruit durian (Durio zibethinus)
Teh BT et al. Nat Genet. 2017 Nov;49(11):1633-1641. doi: 10.1038/ng.3972.

*Pre-print articles available on bioRxiv

A 3-way hybrid approach to generate a new high-quality chimpanzee reference genome (Pan_tro_3.0)
Kuderna LFK et al. Sci Rep. 2017 November 1.

A critical comparison of technologies for a plant genome sequencing project 
Paajanen P et al. 2017 Oct0ber 11; Pre-print*.

Strategies for optimizing BioNano and Dovetail explored through a second reference quality assembly for the legume model, Medicago truncatula
Moll KM et al. BMC Genomics. 2017 August 4.

The impact of third generation genomic technologies on plant genome assembly
Thind AK et al. Nat Biotechnol. 2017 August.

The house spider genome reveals an ancient whole-genome duplication during arachnid evolution
Schwager EE et al. BMC Biol. 2017 July 31.

The Molecular Genetic Basis of Herbivory between Butterflies and their Host-Plants
Nallu S et al. 2017 June 23; Pre-print*.

Improved genome assembly of American alligator genome reveals conserved architecture of estrogen signaling
Rice ES et al. Genome Res. 2017 May.

Improving and correcting the contiguity of long-read genome assemblies of three plant species using optical mapping and chromosome conformation capture data
Jiao WB et al. Genome Res. 2017 May.

Genome assembly with in vitro proximity ligation data and whole-genome triplication in lettuce
Reyes-Chin-Wo S et al. Nat Commun. 2017 April 12.

Genome assembly with in vitro proximity ligation data and whole-genome triplication in lettuce
Laio WB, Schneeberger K. Current Opinion in Plant Biology. 2017 April.

The genome of Chenopodium quinoa
Jarvis DE et al. Nature. 2017 February 16.

De novo hybrid assembly of the rubber tree genome reveals evidence of paleotetraploidy in Hevea species
Pootakham W et al. Sci Rep. 2017 February 2.

The draft genome of tropical fruit durian (Durio zibethinus)
Teh BT et al. Nat Genet. 2017 November.