Dovetail’s Proximity Ligation Technologies

Chicago™ and Dovetail™ Hi-C are the fast and affordable way to span distances up to the size of whole chromosomes.

Chicago and Dovetail Hi-C for scaffolding take short-read data from next-generation sequencing and combines it with long-range information.  By using the read pairs generated by proximity ligation of DNA in chromatin, we can dramatically increase the scaffold contiguity and accuracy of assemblies. More importantly, these technologies are fast and affordable, making them a practical option for everyone.


Chicago and Dovetail Hi-C Library Preparation

 


HiRise™ Scaffolding Pipeline


Suddenly, solving complex problems involving de novo assembly, structural variation, microbiome analysis, cancer research, and phasing analysis becomes much simpler.