You’ve been looking for a better way to understand the underlying genomics of human disease. It’s here now.

Dovetail Genomics has proven technology and software that can accelerate your research into human diseases such as oncology, inherited, and undiagnosed diseases.

With the combination of our industry leading proximity ligation techniques and analysis software we can now reveal all classes of large structural variants and 3D features in the human genome.

We’re bringing you new places to look as well. Fix-C™ with Selva™ software can reveal large variants from FFPE samples that were previously not considered to contain long-range information.

For other sample types such as blood or fresh frozen tissue, you have a choice. Dovetail™ Hi-C Kits allow you to produce high-quality proximity ligation libraries in your own lab, or you can send us your samples and we will take them all the way through analysis.

Seeing and resolving all classes of structural variation is one of the biggest challenges in human disease. We’ve solved it.

There is a growing focus on large structural variants and their role in cancer and other diseases. Current technologies can find structural variants you already know exist, or only identify variants from some classes, such as copy number variations.

What you’ve been missing is a tool that can find and resolve all classes of large structural variants, including balanced and complex variants, across the entire genome.

You can see past the barriers with Fix-C™ for FFPE and Dovetail™ Hi-C for all other sample types. We’ve demonstrated a mastery of proximity ligation in our market-leading services for genome assembly. Now we’ve fine-tuned it to detect large structural variants and 3D features that other methods cannot see.

With results from Selva™ analysis, you’ll be able to see the full spectrum of genomic features—from actionable variants to features that have never been described—at a level of complexity that’s unprecedented. We believe the impact on cancer and other human disease research will be enormous.

FFPE is the de facto archival material for biopsy specimens. For the first time, we can help you see structural variants and 3D features on a genome-wide scale in FFPE.

Think of how many decades of paraffin-embedded biopsy specimens are available in research facilities. How much further could you advance disease research if there was a way to learn more from them? We’re giving you the ability to do just that with Fix-C™ and Selva™ analysis. Reveal previously undetectable structural variants and 3D chromatin features in FFPE samples, and take your research—and our global understanding of the genome—to a whole new level.

Featured Resources

Webinar

Structural Variation Detection by Proximity Ligation from FFPE Tumor Tissue

Dr. Helio Costa, PhD 
Stanford University

Watch the Webinar

Tech Sheet

Profile all classes of large variants from FFPE and other sample types

Fix-C™ and Dovetail™ Hi-C with Selva™ Structural Variant Detection identifies large structural variants of all classes, including balanced and complex variants with no upper limit on the size of the variant from all sample types, including FFPE.

See the Tech Sheet

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We can help you advance research into human disease. Just ask.

Contact us to discover more about this breakthrough technology and how it can help you see further into human disease.

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